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KMID : 0882419930440010058
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Korean Journal of Medicine
1993 Volume.44 No. 1 p.58 ~ p.68
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The Effects of Coronary Sinus Intervention on Myocardial Perfusion Assessed by Myocardial Contrast Echocardiography
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손대원
박승우/김철호/오병희/이명묵/박영배/최윤식/서정돈/이영우
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Abstract
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ackground : during the past three decades there have been renewed interests in using the coronary sinus intervention to treat jeopardized myocardium. Mechanisms and effects of coronary sinus intervention have been studied by the
techniques,
application of which in vivo and in real time is not possible. Recently myocardial contrast echocardiography(MCE) has been shown to be able to offer unique capability of assessing the dynamic pattern of myocardial perfusion.
Methods : MCE was performed in 7 open chest dogs with the intraaortic injection of
hand-agitated contrast agent (hexabrix). Risk area and myocardial perfusion patterns were
analized during coronary artery occlustion only, coronary artery occlustion with coronary sinus
occlustion (CSO) and during rapid relpease of CSO. Also we observed myocardial perfusion
pattern of coronary sinus retroperfusion during coronary artery occlustion.
Results :
1) myocardial contrast echocardiography did not change the hemodynamic parameters.
2) ischemic risk area during coronary artery occlusion with CSO was significantly (p<0.05)
smaller than that measured during coronary artery occlustion only.
3) contrast washout was not enhanced during rapid release of cornary sinus occlusion
compared to the basal status. So miking effect could not be demonstrated in this study.
4) during coronary artery occlusion, coronary sinus retroperfusion of contrast agent showed
selective echo enhancement in ischemic risk area.
Conclusion : coronary sinus intervention is effective in reducing the ischemic risk area
during coronary artery occlustion and its effect can be evaluated by MCE without significant
hemodynamic changes.
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KEYWORD
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